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Fiction · 2015 · PG-13

Inside the O'briens

by Lisa Genova

A Boston police officer is diagnosed with Huntington's disease — and each of his four adult children must decide whether to be tested.

Patrol officer Joe O'Brien is third-generation Irish in Charlestown. A tough cop with a soft interior, a loving wife and four adult children, Joe is diagnosed with Huntington's disease. As Joe's symptoms worsen and he's eventually stripped of his badge and more, Joe struggles to maintain hope and a sense of purpose, while his daughter Katie and her siblings must find the courage to either live a life "at risk" or learn their fate. "From award-winning, New York Times bestselling author and neuroscientist Lisa Genova comes a powerful new novel that does for Huntington's Disease what her debut S

For14+GenreFictionLength326 pagesRead time~8.5 hours

This analysis was generated by AI from publicly available reader reviews, literary criticism, and book discussions. It has not been verified by a BookLens community reviewer and may contain errors. Be the first to verify →

Content snapshot

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What's in this book, at a glance — five things readers want to know before they start.

Violence

Barely any

No significant violence; the disease's physical effects on the body are depicted

Language

Barely any

Mild language in the family drama tradition

Sexual Content

Barely any

Brief adult references

Substance Use

None

No substance use

Emotional Intensity

A lot

Very heavy psychological themes: Huntington's progression, the 50% inheritance odds, and watching a parent deteriorate

What this book is about

Lisa Genova's novel about Huntington's disease hits as hard as Still Alice. The degenerative disease's progression and the family's impossible choices are depicted with clinical and emotional precision. Adult readers.

Notes for sensitive readers

Reader-flagged moments and themes that may affect your experience.

Degenerative disease

Genetic testing dilemma

Psychological weight

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